It’s rather shocking to me how many presumably-intelligent people say neuroscience is “quack science.” In the first place it’s still a young science, as sciences go. But if many theories (or “sub-theories”) turn out to be wrong, or severely incomplete, that doesn’t disqualify the validity of neuroscience, which is the study of how the nervous system — including the brain — works. Scientists develop theories about this, and prove, improve, or disprove them depending on new discoveries that they make. And then, of course, we utilize the results.
Great stuff has already come out of neuroscience. And speaking from personal experience, that includes some of the much-maligned anti-depressant medications, which can turn a life that has become extremely unpleasant into one that can be downright enjoyable and experienced as being worth the living.
This is wonderful news indeed.
From Scientific American.
New Drugs May Transform Down Syndrome
Recent breakthroughs may lead to pharmacological treatments for the chromosomal disorder
Mar 1, 2014 |By Jenni Laidman
‘People born with Down syndrome have always been considered to be incurably developmentally delayed—until now. In the past few years a number of laboratories have uncovered critical drug targets within disabled chemical pathways in the brain that might be restored with medication. At least two clinical trials are currently studying the effects of such treatments on people with Down syndrome. Now geneticist Roger Reeves of Johns Hopkins University may have stumbled on another drug target—this one with the potential to correct the learning and memory deficits so central to the condition.
‘Down syndrome occurs in about one in 1,000 births annually worldwide. It arises from an extra copy of chromosome 21 and the overexpression of each of the 300 to 500 genes the chromosome carries. “If you go back even as recently as 2004, researchers didn’t have much of a clue about the mechanisms involved in this developmental disability,” says Michael Harpold, chief scientific officer with the Down Syndrome Research and Treatment Foundation. But all that has changed. “In the past six or seven years there have been several breakthroughs—and ‘breakthroughs’ is not by any means too big a word—in understanding the neurochemistry in Down syndrome,” Reeves says. [ ... ]‘
Scientific American The article continues with a description of the subject research.